PUFAs Cause Post-prandial Slump

PUFAs block Glycolysis. PUFAs block Glycolysis. PUFAs block Glycolysis.

[edited this into the last post, but it deserves repeating]

u/loveofworkerbees on r/saturatedfat pointed out a prediction I had not made:

I mean this is anecdotally true for me. A year ago eating fruit would put me into a coma. Now 1 year almost no PUFA I get sustained energy from fruit alone. It’s actually really fucking crazy. If it’s placebo effect whatever but it’s night and day for me.

Everyone knows that if you give kids sugar they go crazy with energy.

Obviously: “Crikey a load of excellent fuel has just turned up all at once, Oh God the thing’s over-revving. Throttle Back! Throttle Back!”

And everyone knows that eating a load of carbs makes you tired. In fact it was in hindsight one of the first symptoms of my curse, way back in my thirties. Tired after lunch. But everyone gets tired after lunch, don’t they? Glycaemic Load and all that.

Obviously: “Crikey a load of excellent fuel has just turned up all at once. Better switch over to carbohydrate metabolism. Oh noes, its not working properly (because, and I hate to labour the point, glycolysis is blocked). Oops no enneeeeerrrrrrrrrgggggggyyyyyyyyyyyyyy……

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And so I make the following prediction. Children (and adults) who have eaten nice normal natural foods (and these days that doesn’t even include breast milk, so PUFA-filled are we.) and who have few PUFAs in their systems will get excited on sugar, but not particularly react to starch (which needs a bit of unpacking).

And children (and adults) with masses of PUFA in their systems will slump after eating large quantities of carbs, either sugar or starch.

I got this last night. I am in ketosis. Bouncing energetically around all day. In the evening, choir, teas, milk, biscuits, you know how it goes…. And over the next couple of hours I just felt my mind switch off… This morning I am fine. Bounce. Bounce.

The effect might even be a good proxy for a fat biopsy. I strongly predict a strong correlation here, and if that is not true then one of the things I think I know is wrong.

And it gives me hope, because u/loveofworkerbees has apparently fixed the problem in a year. Maybe there are ways to get the polyunsaturated poison out faster than we think.