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Ministry of Truth's avatar

Have you considered that you might be deficient in molybdenum? There are a few articles on Chris Masterjohns substack about it, especially with regards to Sulfur. Here's one recent free article: https://chrismasterjohnphd.substack.com/p/the-unknown-testosterone-nutrient

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Experimental Fat Loss's avatar

Ha, I have the same finger nail issue. It's actually annoying how fast they grow!

> They're not starvation diets. I think they must function by temporarily making the lipostat mechanism work as intended. Your set-point normalizes, and you just stop eating much because you're not hungry, falling back on stores that the lipostat now realises are excessive.

That's actually interesting to think about in our house heater/AC analogy. Say the thermostat is supposed to be set to 70°F (for people using degrees other than Freedom, this is a comfortable, almost summer-esque temperature).

Several things could be wrong:

1. Maybe the thermostat somehow got set to 93°F

2. Maybe the thermostat is fine, but somebody put ice cubes on or lit a fire under the sensor

3. Pretty much anything else that can go wrong with computers/systems/software could be going wrong

In fact now that I think of it, we know this analogy isn't complex enough. For example, there's a phenomenon PUFAs cause in the mitochondria that's been described by Peter at Hyperlipid forever, and by Fire in a Bottle, too.

This is that the "exhaust gases" of the mitochondria burning fats are part of the feedback signal, the reactive oxygen species, and that burning PUFAs doesn't create them to the same degree as other fats do.

Therefore they don't create sufficient back pressure to cause a cellular "satiety" (=full of energy) signal.

In fact, I think we know that there isn't actually a "temperature sensor" in the body, it's more indirect. I think there are several signals. One of them seems to be leptin, which is elevated the more adipose tissue there is, but can also go too low if you're starved.

Another seems to be that adipose tissue releases fatty acids into the blood, and so you will have fatty acids around at any given time, which can be used for energy and which trigger a certain insulin response. That's why (I think) fat people have high fasting insulin.

It's like they just had a swig of cream at any given time.

I suppose in the house analogy it would be like absence of a temperature sensor, but instead a sensor for furnace/AC exhaust gases. If you choose to burn a fuel that doesn't release the right type of exhaust gases, or not enough (or maybe too much), the sensor will misreport the amount of furnacing/ACing that has actually happened.

So what do we think actually happens in the analogy with ex150? Is the set point set to 93°F, and suddenly gets set back down to 70°F? We know that I'm putting less or no new PUFA-fuel into my tank, but that there's still some old one left in there. I am putting plenty of good fuel in there to balance it, but I was doing that before and it never helped me lose weight, so that part is not enough for me.

Or is the set point on 70°F the whole time, but protein messes up the sensor/the wire in some other way?

> Also he has no problem with energy levels and his waking body temperature is fine, so whatever broke his lipostat didn't also break his metabolism. How can that be?

98.2 and 98.8 just now (after creamy afternoon coffee) within 5 seconds. I'd argue my metabolism is still broken, just not in the "hypothyroid-esque" way.

> I wonder if carbohydrates are also involved, but that starts to look too complex to be true. A complex theory drawn from not much data is likely just modelling the noise.

Sounds like you can't swamp. I likely can't swamp. Just from a black box perspective, it seems like a fair observation that many people can't swamp.

> I think my next experiment will be a bout of OG ex150ish, to see what happens, but I am open to other suggestions.

Sounds like a good idea. I like to go back to basics, validate my axioms. Plus you might get back down closer to 90kg and then you can stay there, which will feel good :) Have you ever done a full 30 day bout of ex150ish?

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